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Structural Joints: Fibrous Joints

Structural Joints: Fibrous Joints

Fibrous joints are a type of joint where the bones are connected by fibrous connective tissue. These joints provide stability and minimal to no movement between the articulating bones. There are three types of fibrous joints.
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Fibrous Proteins

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Cellular Adaptation IV: Dysplasia and Metaplasia

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Sutures of the Skull

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Related Experiment Video

Updated: May 16, 2026

Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis

Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis

Published on: October 12, 2016

[Fibrous dysplasia].

¹Orthopädische Klinik, Olgahospital, Klinikum Stuttgart, Bismarckstraße 8, 70176, Stuttgart, Deutschland. t.wirth@klinikum-stuttgart.de

|November 27, 2012

Summary

This summary is machine-generated.

Fibrous dysplasia is a bone disease caused by a GNAS gene mutation, leading to weakened bones and potential fractures or deformities. Orthopedic treatments can stabilize fractures and correct deformities, improving patient mobility and quality of life.

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Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis

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Published on: October 12, 2016

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Area of Science:

Orthopedics
Genetics
Pathology

Context:

Fibrous dysplasia is a benign intraosseous tumor disease presenting in monostotic or polyostotic forms.
Associated with dermatological and endocrine features, it is known as McCune-Albright disease.
The condition stems from a postzygotic mutation in the GNAS gene, disrupting osteogenesis.

Purpose:

To summarize the nature of fibrous dysplasia, its genetic basis, and clinical manifestations.
To outline the orthopedic treatment strategies for managing fractures and deformities.
To highlight the potential for improved patient mobility and quality of life through intervention.

Summary:

Fibrous dysplasia involves abnormal bone development due to GNAS gene mutations.
Clinical effects include bone weakening, pain, pathological fractures, and severe deformities impacting mobility.
Orthopedic interventions focus on fracture stabilization, bone strengthening, and correction of deformities.

Impact:

Effective orthopedic management can restore pain-free mobility for many patients.
Treatment strategies aim to improve the quality of life for individuals with severe bone deformities.
Understanding the genetic basis aids in comprehending disease pathogenesis and potential future therapies.