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Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...
Applications Of NMR In Biology01:25

Applications Of NMR In Biology

Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics  for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.
The...

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Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples
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Published on: June 9, 2016

Multifunctional magnetic resonance imaging probes.

Ewelina Kluza1, Gustav J Strijkers, Klaas Nicolay

  • 1Biomedical NMR, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands. E.Kluza@tue.nl

Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer
|November 27, 2012
PubMed
Summary

Multifunctional magnetic resonance imaging (MRI) probes, often nanoparticle-based, enhance cancer diagnostics and therapy. These advanced probes improve tumor detection, drug delivery, and treatment monitoring for personalized oncology.

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Last Updated: May 16, 2026

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples
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Published on: June 9, 2016

Multiple-mouse Neuroanatomical Magnetic Resonance Imaging
09:08

Multiple-mouse Neuroanatomical Magnetic Resonance Imaging

Published on: February 27, 2011

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
17:16

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

Area of Science:

  • Oncology
  • Biomedical Engineering
  • Radiology

Background:

  • Magnetic resonance imaging (MRI) is crucial for cancer diagnostics and monitoring treatment efficacy.
  • Tumor detection and characterization rely on differentiating malignant from healthy tissues using MRI.
  • Contrast agents are commonly used to improve MRI signal differences, but novel approaches are emerging.

Purpose of the Study:

  • To review the current state and recent advancements in multifunctional MRI probes for oncology.
  • To highlight the potential of these probes in improving tumor diagnosis and treatment strategies.
  • To discuss the design principles and applications of novel nanoparticle-based MRI probes.

Main Methods:

  • Review of recent literature on multifunctional MRI probes in cancer research.
  • Analysis of nanoparticle design strategies for enhanced biodistribution and tumor targeting.
  • Exploration of multimodal imaging and therapeutic integration within single probes.

Main Results:

  • Multifunctional MRI probes offer tailored composition, size, and surface properties for improved tumor delivery.
  • These probes can integrate multiple imaging modalities and therapeutic agents.
  • Optimized delivery to the tumor microenvironment is achievable via passive or targeted mechanisms.

Conclusions:

  • Multifunctional MRI probes represent a significant advancement in oncology, enabling more specific tumor diagnosis.
  • They facilitate patient-specific treatment planning and monitoring of local drug delivery.
  • Early evaluation of therapy effectiveness can be enhanced using these innovative probes.