Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lung function in patients with prior poliomyelitis.

K Borg1, L Kaijser

  • 1Department of Neurology, Karolinska Hospital, Stockholm, Sweden.

Clinical Physiology (Oxford, England)
|March 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Vision therapy as part of neurorehabilitation after acquired brain injury - a clinical study in an outpatient setting.

Brain injury·2020
Same author

Correction: Standardisation and consensus guidelines for minimal residual disease assessment in Philadelphia-positive acute lymphoblastic leukemia (Ph+ALL) by real-time quantitative reverse transcriptase PCR of e1a2 BCR-ABL1.

Leukemia·2020
Same author

Standardisation and consensus guidelines for minimal residual disease assessment in Philadelphia-positive acute lymphoblastic leukemia (Ph + ALL) by real-time quantitative reverse transcriptase PCR of e1a2 BCR-ABL1.

Leukemia·2019
Same author

Performance and digestive function of broiler chickens given grit in the diet.

British poultry science·2017
Same author

Polio Patients in Northern Italy, a 50 Year Follow-up.

The open neurology journal·2016
Same author

Peroxiredoxin VI oxidation in cerebrospinal fluid correlates with traumatic brain injury outcome.

Free radical biology & medicine·2014
Same journal

LETTER TO THE EDITOR: Does cardiac output determine leg blood-flow?

Clinical physiology (Oxford, England)·2017
Same journal

REPLY TO LETTER TO THE EDITOR.

Clinical physiology (Oxford, England)·2017
Same journal

The static pressure-volume relationship of the respiratory system determined with a computer-controlled ventilator.

Clinical physiology (Oxford, England)·2009
Same journal

How well does journal 'impact' work in the assessment of papers on clinical physiology and nuclear medicine?

Clinical physiology (Oxford, England)·2009
Same journal

Oral contraceptives elevate core temperature and heart rate during exercise in the heat.

Clinical physiology (Oxford, England)·2009
Same journal

Cardiac secretion of atrial and brain natriuretic peptides in acute ischaemic heart failure in pigs: effect of angiotensin II receptor antagonism.

Clinical physiology (Oxford, England)·2009
See all related articles

Prior polio patients exhibit reduced lung volumes and respiratory muscle strength, leading to restrictive lung dysfunction and hypoventilation. This study highlights the impact of respiratory muscle weakness on lung function in polio survivors.

Area of Science:

  • Pulmonary Medicine
  • Neuromuscular Disorders
  • Respiratory Physiology

Background:

  • Poliomyelitis can cause significant respiratory muscle weakness.
  • The long-term impact of polio on respiratory mechanics requires further investigation.

Purpose of the Study:

  • To assess lung volumes, spirometric flows, respiratory pressures, diffusion capacity, and blood gases in polio survivors.
  • To compare respiratory function in polio patients with a healthy control group.
  • To determine the relationship between respiratory muscle strength and lung function in polio survivors.

Main Methods:

  • Evaluated lung volumes, spirometry, maximal respiratory pressures, lung diffusion capacity, and arterial blood gases.
  • Compared data from 20 polio patients with an age- and sex-matched control group.

Related Experiment Videos

Main Results:

  • Polio patients showed significantly reduced static lung volumes and pulmonary flow capacity (~65% of controls).
  • Maximal respiratory pressures were significantly lower in polio patients, impacting lung-flow capacity.
  • Polio patients had increased PCO2, indicating alveolar hypoventilation, inversely correlated with respiratory pressures.

Conclusions:

  • Findings suggest restrictive respiratory dysfunction and alveolar hypoventilation in polio survivors.
  • Respiratory muscle weakness is the likely cause of impaired lung function post-polio.
  • Maximal respiratory pressures are critical determinants of lung-flow capacity, especially with decreased muscle force.