Related Experiment Video
Updated: May 16, 2026

A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds
Published on: February 23, 2024
Pediatric burn injuries
Vijay Krishnamoorthy1, Ramesh Ramaiah, Sanjay M Bhananker
1Department of Anesthesiology and Pain Medicine, University of Washington School of Medicine, Seattle, WA, USA.
Insights
Pediatric burn care requires intensive medical and surgical therapy for multisystemic effects and pain management. Specialized burn centers with multidisciplinary teams offer optimal treatment for severe pediatric thermal injuries.
Area of Science:
- Pediatric medicine
- Trauma surgery
- Burn management
Background:
- Pediatric burns are a significant global health issue, caused by scalds, fire, or abuse.
- Burn severity is classified by body surface area and depth, impacting multiple organ systems.
Purpose of the Study:
- To review the critical components of pediatric burn care.
- To highlight pathophysiologic consequences, circulatory, respiratory, surgical, and pain management strategies.
Main Methods:
- This is a review article, synthesizing current knowledge on pediatric burn management.
- It emphasizes the multidisciplinary approach in specialized burn centers.
Main Results:
- Large burn injuries lead to multisystemic manifestations requiring intensive support.
- Effective management involves medical therapy for organ dysfunction and surgical intervention to prevent complications like sepsis.
Conclusions:
- Comprehensive burn care is essential for critically ill pediatric patients.
- Specialized burn centers provide the optimal environment for managing severe thermal injuries in children.
Abstract:
Pediatric burns comprise a major mechanism of injury, affecting millions of children worldwide, with causes including scald injury, fire injury, and child abuse. Burn injuries tend to be classified based on the total body surface area involved and the depth of injury. Large burn injuries have multisystemic manifestations, including injuries to all major organ systems, requiring close supportive and therapeutic measures. Management of burn injuries requires intensive medical therapy for multi-organ dysfunction/failure, and aggressive surgical therapy to prevent sepsis and secondary complications. In addition, pain management throughout this period is vital. Specialized burn centers, which care for these patients with multidisciplinary teams, may be the best places to treat children with major thermal injuries. This review highlights the major components of burn care, stressing the pathophysiologic consequences of burn injury, circulatory and respiratory care, surgical management, and pain management of these often critically ill patients.
Related Concept Videos
Burn Injuries
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Pharmacokinetics in Pediatric Patients: Drug Metabolism
Drug Dosing: Infants and Children
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Pharmacokinetics in Pediatric Patients: Drug Distribution
Pharmacokinetics in Pediatric Patients: Drug Excretion

