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Related Concept Videos

Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Drug Toxicity: Allergic Reactions01:30

Drug Toxicity: Allergic Reactions

Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics01:23

Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics

Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla.  Benzonatate operates peripherally within the respiratory tract by anesthetizing...
Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...

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Related Experiment Video

Updated: May 16, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Pregnancy and dermatologic therapy.

Kelly H Tyler1, Matthew J Zirwas1

  • 1Division of Dermatology, Ohio State University, Columbus, Ohio.

Journal of the American Academy of Dermatology
|November 28, 2012
PubMed
Summary
This summary is machine-generated.

Dermatologists must understand medication safety during pregnancy. Topical treatments are preferred, but some systemic drugs and second-trimester dermatologic surgery are safe when necessary for pregnant patients.

Related Experiment Videos

Last Updated: May 16, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Area of Science:

  • Dermatology
  • Obstetrics
  • Pharmacology

Background:

  • Dermatologic conditions affect pregnant women.
  • Safe prescribing during pregnancy is crucial for maternal and fetal health.
  • Dermatologists require guidance on managing skin conditions in pregnant patients.

Purpose of the Study:

  • To review medication safety in pregnancy for dermatologic conditions.
  • To provide guidance on safe treatment options for pregnant women.
  • To outline recommendations for dermatologic procedures during pregnancy.

Main Methods:

  • Literature review on dermatologic treatments and pregnancy.
  • Analysis of medication safety data for common dermatologic drugs.
  • Guidelines for surgical procedures in pregnant patients.

Main Results:

  • Topical medications are the first-line therapy for pregnant women.
  • Certain systemic medications are considered safe for use during pregnancy.
  • Dermatologic surgery can be performed in the second trimester with specific precautions.

Conclusions:

  • Dermatologists must be knowledgeable about pregnancy medication safety.
  • A stepwise approach to treatment, starting with topicals, is recommended.
  • Careful consideration and patient counseling are essential for managing dermatologic conditions during pregnancy.