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[Persistent genital arousal disorder: a systematic review].

T Thubert¹, M Brondel, M Jousse

¹GREEN Groupe de recherche clinique en neuro urologie, université Pierre-et-Marie-Curie, 75020 Paris, France. thibault.thubert@gmail.com

Progres En Urologie : Journal De L'Association Francaise D'Urologie Et De La Societe Francaise D'Urologie

|November 28, 2012

Summary

Persistent genital arousal disorder (PGAD) affects 1% of the population and is linked to overactive bladder and restless legs syndrome. Management requires a multidisciplinary approach for effective treatment.

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Area of Science:

Gynecology
Urology
Neurology

Background:

Persistent genital arousal disorder (PGAD) is a newly recognized condition.
Proper recognition of PGAD is crucial to avoid misdiagnosis and inappropriate labeling of affected individuals.

Purpose of the Study:

To provide guidance on the recognition and management of Persistent Genital Arousal Disorder (PGAD).
To highlight the importance of avoiding psychological misinterpretations of PGAD symptoms.

Main Methods:

A comprehensive literature review was conducted using major databases (PubMed, Medline, Embase, Cochrane).
Search terms included "persistent genital arousal", "restless genital syndrome", "persistent genital arousal syndrome", and "persistent sexual arousal syndrome".
37 articles out of 300 reviewed were found to be relevant to PGAD.

Main Results:

PGAD prevalence is estimated at 1%, potentially more common than previously suspected.
Associated conditions include overactive bladder (OAB), restless legs syndrome (RLS), and pelvic varices.
Genital sensations are described as unwanted and intrusive, often occurring at the clitoris, labia, or vagina.

Conclusions:

This review offers guidance for clinicians in managing patients with PGAD.
A multidisciplinary approach involving history, examination, and investigations like pelvic MRI is recommended.
Treatment options include psychological therapies, psychotropic medications (e.g., clonazepam), and transcutaneous electrical nerve stimulation (TENS).