Related Experiment Video

Updated: May 16, 2026

Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle
09:40

Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle

Published on: January 19, 2017

[Metabolic abnormalities and relationship with cardiovascular risk factors in children]

Santiago Manuel Palacios-Mancilla1, Miguel Angel Rubio-Lezama, Margarito de Jesús de la Torre-López

  • 1Instituto Mexicano del Seguro Social, Tlalnepantla de Baz, Estado de México, Mexico. spalacios_21@hotmail.com

Revista Medica Del Instituto Mexicano Del Seguro Social
|November 28, 2012
PubMed

Insights

Family history of cardiovascular disease significantly impacts pediatric metabolic health. This study in children highlights the link between genetic predisposition and metabolic abnormalities, emphasizing early screening.

Area of Science:

  • Pediatric Cardiology
  • Metabolic Health
  • Cardiovascular Risk Factors

Context:

  • Cardiovascular risk factors are increasingly prevalent in pediatric populations.
  • Metabolic abnormalities in children can lead to long-term health issues.
  • General Hospital Zone 58 serves a diverse pediatric patient group.

Purpose:

  • To identify cardiovascular risk factors in pediatric patients.
  • To investigate the relationship between these risk factors and metabolic abnormalities.
  • To assess the influence of lifestyle and family history on pediatric metabolic health.

Summary:

  • A study of 30 children revealed that 90% had at least one abnormal laboratory result.
  • Key cardiovascular risk factors identified include birth weight, television viewing hours, sleep duration, and junk food consumption.
  • Body Mass Index (BMI) variations were noted, with several children falling outside the normal percentile range.
  • Family history of cardiovascular disease or lipid disorders emerged as the primary determinant of metabolic disorders.

Impact:

  • Findings underscore the importance of early screening for cardiovascular risk factors in children.
  • Highlights the significant role of genetic predisposition in pediatric metabolic health.
  • Informs targeted interventions for preventing cardiovascular disease in young populations.
Abstract

More Related Videos

Assessment of Child Anthropometry in a Large Epidemiologic Study09:36

Assessment of Child Anthropometry in a Large Epidemiologic Study

Published on: February 2, 2017

Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
Inborn Errors of Metabolism01:20

Inborn Errors of Metabolism

Phenylketonuria (PKU) is a protein metabolism disorder characterized by high blood levels of the amino acid phenylalanine. This results from a mutation in the gene responsible for phenylalanine hydroxylase, an enzyme that converts phenylalanine into tyrosine. When this enzyme is deficient, phenylalanine builds up in the blood, leading to symptoms such as vomiting, rashes, seizures, growth deficiency, and severe mental retardation. An early diagnosis and a diet restricting phenylalanine intake...
Type II Diabetes I: Introduction01:26

Type II Diabetes I: Introduction

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, in which target tissues such as the liver, muscle, and adipose tissue respond poorly to insulin. It is also associated with inadequate compensatory insulin secretion, where pancreatic β-cells fail to produce sufficient insulin. Together, these abnormalities lead to persistent hyperglycemia.EtiologyT2DM develops through a complex interaction of genetic predisposition and environmental or...
Overview of Carbohydrate Metabolism01:19

Overview of Carbohydrate Metabolism

Carbohydrate metabolism is a fundamental biochemical process that ensures a constant supply of energy to living cells. The most important carbohydrate is glucose, which can be broken down via glycolysis to enter into the Krebs cycle and eventually lead to the production of ATP through oxidative phosphorylation.
Glucose transport into cells is facilitated by a family of transport proteins called GLUT (Glucose Transporters). GLUT4 is the primary glucose transporter for insulin-stimulated glucose...
Overview of Lipid Metabolism01:24

Overview of Lipid Metabolism

Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...