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Age-related changes in rat liver phospholipid transfer activity
T T Markovska1, D H Petkova, A B Momchilova-Pankova
1Central Laboratory of Biophysics, Bulgarian Academy of Sciences, Sofia.
Experimental Gerontology
|January 1, 1990
Abstract:
The age-induced changes in the liver cytosol phospholipid transfer activity of male and female rats have been investigated. These changes were found to be closely related to the age-induced alterations in the two major microsomal phospholipids--phosphatidylcholine and phosphatidylethanolamine. Regression analysis indicated a linear correlation between the phospholipid transfer activity and the level of phosphatidylcholine (positive) and phosphatidylethanolamine (negative) in liver microsomes of both male and female rats.