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Increased glucose use in the hypoglossal nucleus after hypoglossal nerve transection in aged rats
1Research Service, Kansas City Veterans Affairs Medical Center, Missouri 64128.
Experimental Neurology
|April 1, 1990
Abstract:
We used [2-14C]deoxyglucose as a marker of increased metabolism of the hypoglossal nucleus after transection of its nerve. We studied this metabolism in 3-, 12-, and 24-month-old rats. We found an increase in glucose uptake in the control nucleus of 24-month-old rats which was significant when compared to that of 3-month-old rats. We also found a twofold increase in the difference between glucose uptake on the side of nerve transection compared to the control side in old rats.