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Published on: November 21, 2025
Attempted endoscopic closure of a pancreaticocolonic fistula with an over-the-scope clip
Darrell M Gray1, Daniel K Mullady
1Department of Medicine, Washington University School of Medicine. St. Louis, MO, USA. dgray@dom.wustl.edu
Context:
Spontaneous development of fistulae is an uncommon complication of acute pancreatitis. Until recently, surgical management has been the standard of care. Endoscopic treatment has been described with hemoclips and glue.
Case Report:
We report a case of a gentleman with a history of recurrent episodes of acute pancreatitis who presented with symptoms correlating with the development of a pancreatic-colonic fistula. Closure of the fistula was attempted with an over-the-scope clip.
Conclusion:
More evidence is needed to determine criteria for use of over-the-scope clip in closure of GI and pancreatic fistulae.

