Related Experiment Video

Updated: May 16, 2026

Characterizing Salmonella Typhimurium-induced Septic Peritonitis in Mice
14:10

Characterizing Salmonella Typhimurium-induced Septic Peritonitis in Mice

Published on: July 29, 2022

Recurrent meningitis due to Salmonella enteritidis: a case report from Kashmir India

B A Fomda1, B A Charoo, J A Bhat

  • 1Department of Microbiology, Sher-I-Kashmir Institute of Medical Sciences, Soura, Srinagar, India.

Indian Journal of Medical Microbiology
|November 28, 2012
PubMed

Insights

Recurrent bacterial meningitis in infants, caused by Salmonella enteritidis, can reappear weeks after initial treatment. This case highlights the need for physician awareness regarding potential relapse despite initial antibiotic success.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Microbiology

Background:

  • Recurrent bacterial meningitis poses significant risks to infants, including life-threatening complications and psychological distress from repeated hospitalizations.
  • Salmonella enteritidis is a recognized cause of bacterial meningitis, particularly in neonates and young infants.

Observation:

  • A one-month-old infant presented with recurrent meningitis.
  • Cerebrospinal fluid (CSF) and blood cultures initially identified Salmonella enteritidis.
  • The infant received a 3-week course of intravenous ciprofloxacin and ceftriaxone, showing initial improvement and becoming afebrile.

Findings:

  • Despite apparent successful treatment, the infant was readmitted 28 days post-discharge with fever and refusal to feed.
  • Repeat blood and CSF cultures again confirmed the presence of Salmonella enteritidis, indicating treatment failure or relapse.
  • This recurrence occurred despite a full course of appropriate antibiotics.

Implications:

  • Physicians must be educated about the potential for recurrent bacterial meningitis, even weeks after seemingly effective antibiotic therapy.
  • This case underscores the importance of vigilant follow-up and consideration of relapse in pediatric meningitis patients.
  • Further research into optimal treatment durations and management strategies for recurrent Salmonella meningitis in neonates is warranted.

More Related Videos

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery10:03

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery

Published on: November 5, 2019

Chronic Salmonella Infection Induced Intestinal Fibrosis08:40

Chronic Salmonella Infection Induced Intestinal Fibrosis

Published on: September 22, 2019

Related Concept Videos

Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Reservoir of Infection01:30

Reservoir of Infection

Infectious diseases arise from intricate interactions between pathogens and their reservoirs. A reservoir of infection refers to the natural habitat where a pathogen lives, grows, and multiplies, serving as a continual source of infection. Reservoirs are broadly classified as either living or nonliving, and each plays a unique role in disease transmission, significantly influencing public health interventions and control strategies.Humans act as reservoirs for a wide array of pathogens,...
Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
Encephalitis l: Introduction01:19

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...