Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Supervised withdrawal of long-term digoxin therapy.

J F Fair1

  • 1Department of General Practice, Edinburgh University, Scotland.

Family Practice
|March 1, 1990
PubMed
Summary

Discontinuing digoxin under supervision successfully stopped unnecessary treatment in 44% of patients. Digoxin withdrawal was more successful in patients with sinus rhythm than atrial fibrillation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hospital discharge and death communications.

British journal of hospital medicine·1989
Same author

Delayed communication between hospitals and general practitioners.

BMJ (Clinical research ed.)·1988
Same author

Staphylococcus aureus in domestic animals.

Public health reports (Washington, D.C. : 1896)·1961
See all related articles

Area of Science:

  • Cardiology
  • Pharmacology
  • Clinical Practice

Background:

  • Digoxin is a commonly prescribed medication for various cardiac conditions.
  • Assessing the continued need for digoxin therapy is crucial for optimizing patient care and resource allocation.

Purpose of the Study:

  • To evaluate the feasibility and outcomes of supervised digoxin withdrawal in a primary care setting.
  • To determine factors influencing successful discontinuation of digoxin therapy.

Main Methods:

  • A prospective study involving 32 patients on long-term digoxin therapy.
  • Supervised withdrawal of digoxin followed by clinical assessment and monitoring.
  • Analysis of patient data based on cardiac rhythm (sinus rhythm vs. atrial fibrillation) and clinical outcomes.

Main Results:

  • Digoxin was successfully discontinued in 44% (14/32) of patients.
  • In 56% (18/32) of cases, digoxin was necessary and restarted due to clinical deterioration.
  • Successful withdrawal rates were significantly higher in patients with sinus rhythm (91%) compared to those with atrial fibrillation (19%).
  • Dosage adjustments were often required to achieve optimal control when digoxin remained necessary.

Conclusions:

  • Supervised withdrawal of digoxin is a viable strategy to identify and discontinue unnecessary therapy.
  • Patient's underlying cardiac rhythm is a key predictor of successful digoxin discontinuation.
  • Implementing a structured protocol for digoxin management can improve patient care and reduce healthcare costs.

Related Experiment Videos