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Isolated left ventricular non-compaction controversies in diagnostic criteria, adverse outcomes and management

Paaladinesh Thavendiranathan1, Arun Dahiya, Dermot Phelan

  • 1Department of Cardiology, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

Heart (British Cardiac Society)
|November 28, 2012
PubMed

Insights

Isolated left ventricular non-compaction (LVNC) is a heart muscle disorder. This review clarifies diagnostic criteria and management strategies for LVNC, addressing current controversies in cardiovascular imaging.

Area of Science:

  • Cardiology
  • Medical Imaging

Background:

  • Isolated left ventricular non-compaction (LVNC) is a morphological abnormality characterized by excessive left ventricular trabeculation.
  • LVNC is frequently associated with ventricular dysfunction, arrhythmias, and cardioembolic events.
  • Increased diagnosis of LVNC is driven by advances in cardiovascular imaging technology.

Purpose of the Study:

  • To review current controversies in the clinical diagnosis of LVNC.
  • To provide an evidence-based overview of diagnostic criteria for LVNC.
  • To suggest a management approach for patients with LVNC.

Main Methods:

  • Literature review of recent studies on LVNC diagnosis and management.
  • Analysis of current controversies in clinical diagnosis.
  • Synthesis of data to propose a management strategy.

Main Results:

  • Diagnosis of LVNC is increasing due to improved imaging availability.
  • Diagnostic criteria and management strategies for LVNC remain subjects of debate.
  • Recent studies highlight the utility of novel diagnostic methods and adverse event incidence.

Conclusions:

  • Standardized, evidence-based imaging diagnostic criteria for LVNC are needed.
  • A clear management approach is essential for LVNC.
  • Further research is required to resolve diagnostic and therapeutic controversies.

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