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Related Concept Videos

Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...
Study Designs in Epidemiology01:20

Study Designs in Epidemiology

Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and case-control studies.
Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.

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Related Experiment Video

Updated: May 16, 2026

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population
09:02

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population

Published on: January 31, 2025

Gender differences in osteoporosis screening: retrospective analysis.

Khaled Alswat1, Suzanne Myers Adler

  • 1Division of Endocrinology, Washington DC Veterans Affairs Medical Center, George Washington University, Washington, DC, USA. dr_kswat@hotmail.com

Archives of Osteoporosis
|November 28, 2012
PubMed
Summary

Men are screened for osteoporosis less often than women, despite similar prevalence. This study highlights a significant gender disparity in osteoporosis screening rates, indicating a need for improved screening protocols in men.

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Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

Related Experiment Videos

Last Updated: May 16, 2026

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population
09:02

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population

Published on: January 31, 2025

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

Area of Science:

  • Endocrinology
  • Geriatrics
  • Public Health

Background:

  • Osteoporosis affects 20% of men and causes over 1.5 million fractures annually in the USA.
  • Complications from hip fractures lead to death in up to 20% of patients within 12 months.
  • The Endocrine Society recommends osteoporosis screening for all men aged 70+.

Purpose of the Study:

  • To investigate gender differences in osteoporosis screening rates.
  • To compare osteoporosis screening uptake between males and females in an outpatient setting.

Main Methods:

  • Retrospective study conducted at a university-based outpatient clinic.
  • Included males aged 70-75 and females aged 65-70 with a primary care physician.
  • Analyzed data from patients with at least one routine health maintenance exam since 2002.

Main Results:

  • 8,262 patients were identified (39.4% male, 60.6% female).
  • Osteoporosis screening rates were 18.4% for males (63/342) and 60% for females (402/668).
  • Significant gender disparity observed in DXA scan utilization for screening.

Conclusions:

  • Males are screened for osteoporosis less frequently than females.
  • This disparity exists despite comparable prevalence of osteoporosis between genders.
  • Highlights a need to address gender-specific screening gaps.