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Related Experiment Video

Updated: May 16, 2026

An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components
08:17

An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components

Published on: July 18, 2018

Emerging technologies for assembly of microscale hydrogels.

Umut Atakan Gurkan1, Savas Tasoglu1, Doga Kavaz1

  • 1Bio-Acoustic MEMS in Medicine (BAMM) Laboratory Center for Bioengineering Brigham and Women's Hospital Harvard Medical School Boston, MA 02115, USA.

Advanced Healthcare Materials
|November 28, 2012
PubMed
Summary

Microscale hydrogel assembly enables complex 3D tissue engineering for regenerative medicine and drug discovery. Novel methods offer rapid, scalable fabrication of engineered tissue constructs with controlled microarchitectures.

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Gelatin Methacryloyl Granular Hydrogel Scaffolds: High-throughput Microgel Fabrication, Lyophilization, Chemical Assembly, and 3D Bioprinting
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Last Updated: May 16, 2026

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An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components

Published on: July 18, 2018

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning
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Gelatin Methacryloyl Granular Hydrogel Scaffolds: High-throughput Microgel Fabrication, Lyophilization, Chemical Assembly, and 3D Bioprinting
10:36

Gelatin Methacryloyl Granular Hydrogel Scaffolds: High-throughput Microgel Fabrication, Lyophilization, Chemical Assembly, and 3D Bioprinting

Published on: December 9, 2022

Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Regenerative Medicine

Background:

  • Cell encapsulating microscale hydrogels are crucial for regenerative medicine, tissue engineering, and in vitro assays.
  • Tissue engineering aims to replicate native tissue complexity by organizing microscale building blocks.

Purpose of the Study:

  • To review emerging microscale hydrogel assembly methods for 3D construct fabrication.
  • To discuss the potential applications and future perspectives of these technologies.

Main Methods:

  • Survey of novel assembly technologies including microfluidics, acoustic/magnetic fields, nanotextured surfaces, and surface tension.
  • Focus on methods enabling rapid and scalable microgel assembly in three dimensions.

Main Results:

  • Engineered tissue constructs with controlled microarchitectural and compositional features can be fabricated.
  • Emerging technologies offer high-throughput and scalable solutions for 3D microarchitecture assembly.

Conclusions:

  • Microscale hydrogel assembly is advancing tissue engineering and pharmaceutical research.
  • Future perspectives involve developing more sophisticated and scalable assembly methods for complex 3D constructs.