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Updated: May 16, 2026

Contrast Enhanced Vessel Imaging using MicroCT
Published on: January 27, 2011
Hybrid BaYbF(5) nanoparticles: novel binary contrast agent for high-resolution in vivo X-ray computed tomography
Yanlan Liu1, Kelong Ai, Jianhua Liu
1State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, PR China.
Abstract:
A novel CT contrast agent denoted as BaYbF(5) @SiO(2) @PEG is presented. The as-prepared nanoparticles exhibit significantly enhanced contrast efficacy relative to clinical iodinated agents and maintain higher X-ray attenuation at different voltages, suitable for diagnostic imaging of various patients. Prolonged circulation time in vivo and low toxicity mean the nanoparticles perform excellently in in-vivo X-ray CT angiography.
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