Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
Metastasis02:30

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Cancer02:18

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Investigating Person-Job Fit, Job Performance, Psychological Capital, and Job Burnout Among Pre-Hospital Emergency Personnel: A Cross-Sectional Study.

Health science reports·2026
Same author

The Effect of Trigger-to-Retrieval Time Interval on Assisted Reproductive Technology Outcomes in Patients with Poor Ovarian Response : The Effect of Trigger-to-Retrieval Time Interval on Assisted Reproductive Technology Outcomes.

Galen medical journal·2026
Same author

Iron-oxide nanoparticles (SPIONs) enhance malaria vaccine antibody response.

Vaccine·2026
Same author

Spatio-temporal analysis of tuberculosis prevalence in Iran.

BMC infectious diseases·2026
Same author

Comparative efficacy of two kangaroo care scheduling methods on depressed mood and mental health in birthing parents of preterm infants: a randomized clinical trial.

BMC pregnancy and childbirth·2026
Same author

Investigating the Effect of Endometrial Thickness Changes and Compaction on the Fertility Rate of Patients Undergoing ART: A Prospective Study.

Journal of obstetrics and gynaecology of India·2025

Related Experiment Video

Updated: May 16, 2026

Quail Chorioallantoic Membrane - A Tool for Photodynamic Diagnosis and Therapy
07:43

Quail Chorioallantoic Membrane - A Tool for Photodynamic Diagnosis and Therapy

Published on: April 28, 2022

Tumor inside a pearl drop.

Tina Arbatan1, Aswan Al-Abboodi, Fatemeh Sarvi

  • 1Department of Chemical Engineering, Monash University, VIC 3800, Australia.

Advanced Healthcare Materials
|November 28, 2012
PubMed
Summary
This summary is machine-generated.

Liquid marbles, with their unique structure, can house cancer cell spheroids. This research explores spheroid formation within liquid marbles, opening new paths for cancer research and biomedical applications.

More Related Videos

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells
10:01

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

Published on: August 2, 2022

Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

Related Experiment Videos

Last Updated: May 16, 2026

Quail Chorioallantoic Membrane - A Tool for Photodynamic Diagnosis and Therapy
07:43

Quail Chorioallantoic Membrane - A Tool for Photodynamic Diagnosis and Therapy

Published on: April 28, 2022

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells
10:01

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

Published on: August 2, 2022

Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Cancer Research

Background:

  • Liquid marbles offer a unique microenvironment for biological applications due to their confined internal space and non-adhesive, porous shell.
  • Cancer cells in suspension can self-assemble into three-dimensional structures known as cancer cell spheroids (CCS).

Purpose of the Study:

  • To investigate the formation of cancer cell spheroids (CCS) within the unique environment of a liquid marble.
  • To explore the potential of liquid marbles as a novel platform for cancer research and biomedical applications.

Main Methods:

  • Utilizing liquid marbles as a micro-containment system.
  • Culturing cancer cells in suspension within liquid marbles to observe aggregation and spheroid formation.

Main Results:

  • Demonstrated successful formation of cancer cell spheroids (CCS) within liquid marbles.
  • Highlighted the liquid marble's capability to support and facilitate the development of three-dimensional cancer cell structures.

Conclusions:

  • Liquid marbles provide a promising and innovative scaffold for studying cancer cell spheroids (CCS).
  • This approach presents significant potential for advancing cancer research and developing new biomedical applications.