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Updated: May 16, 2026

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation
Published on: December 8, 2017
Hybrid conducting polymer-hydrogel conduits for axonal growth and neural tissue engineering
Mohammad R Abidian1, Eugene D Daneshvar, Brent M Egeland
1Department of Bioengineering, Pennsylvania State University, University Park, PA 16802, USA. mabidian@psu.edu
Abstract:
Successfully and efficiently bridging peripheral nerve gaps without the use of autografts is a substantial clinical advance for peripheral nerve reconstructions. Novel templating methods for the fabrication of conductive hydrogel guidance channels for axonal regeneration are designed and developed. PEDOT is electrodeposited inside the lumen to create fully coated-PEDOT agarose conduits and partially coated-PEDOT agarose conduits.

