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Updated: May 16, 2026

Expression of Exogenous Antigens in the Mycobacterium bovis BCG Vaccine via Non-genetic Surface Decoration with the Avidin-biotin System
Published on: January 31, 2018
Mimicking the biological ligand-receptor principle for universal target gene delivery mediated by avidin-biotin
1Key Laboratory of Biomedical Polymers of Ministry of Education, & Department of Chemistry, Wuhan University, Wuhan 430072, P. R. China.
Abstract:
A facile and flexible targeting gene-delivery strategy is reported by mimicking the biological ligand-receptor principle based on avidin-biotin interaction. In vitro and in vivo investigations demonstrate that this strategy provides a simple, but universal alternative for potential target gene delivery as well as drug delivery.
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