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Simultaneous ex vivo Functional Testing of Two Retinas by in vivo Electroretinogram System
Published on: May 6, 2015
Assessment of retinal sensitivity using a time-saving strategy in normal individuals
Hirotaka Suzumura1, Keiji Yoshikawa, Shiro Mizoue
1Eye Department, Nakano General Hospital, Tokyo.
Clinical Ophthalmology (Auckland, N.Z.)
|November 28, 2012
Summary
Swedish Interactive Threshold Algorithm Standard (SITA-S) demonstrated higher retinal sensitivity in normal individuals compared to the Dynamic strategy. This visual field testing difference may impact clinical interpretations.
Area of Science:
- Ophthalmology
- Visual field testing
- Retinal sensitivity measurement
Background:
- Visual field testing is crucial for diagnosing and monitoring ophthalmic conditions.
- Standardized algorithms are essential for reliable and comparable visual field data.
- Comparing different visual field testing strategies is important for clinical practice.
Purpose of the Study:
- To compare retinal sensitivities in normal individuals using the Swedish Interactive Threshold Algorithm Standard (SITA-S) on the Humphrey field analyzer versus the Dynamic strategy on the Octopus perimeter.
- To evaluate potential differences in sensitivity measurements between these two common visual field testing algorithms.
Main Methods:
- Standardized background luminance, stimulus size, and exposure time were used for both devices.
- 67 normal individuals (age > 20) underwent visual field examinations using SITA-S (central 30-2 program) followed by Dynamic (32 program).
- Eyes with corrected visual acuity ≥ 0.8, refractive error ≤ -6.0 diopters, and reliable fields were selected for analysis.
Main Results:
- Mean retinal sensitivity was significantly higher with SITA-S (29.0 ± 2.4 dB) compared to Dynamic (26.8 ± 2.1 dB) (P < 0.0001).
- Age-related decline in retinal sensitivity was significantly greater with Dynamic (-0.09 dB/year) than SITA-S (-0.07 dB/year) (P = 0.0003).
- SITA-S showed significantly higher retinal sensitivities across central, mid-peripheral, and peripheral visual field areas (P < 0.0001).
Conclusions:
- The Swedish Interactive Threshold Algorithm Standard (SITA-S) and Dynamic strategies yield different retinal sensitivity values in normal individuals.
- These observed differences in visual field testing may stem from inherent variations in the algorithms' methodologies.
- Understanding these discrepancies is vital for accurate interpretation of visual field test results in clinical settings.
Keywords:
Humphrey field analyzerOctopus perimeterSwedish Interactive Threshold Algorithm Standarddynamicfrequency-of-seeing curvetime-saving strategy
