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Updated: May 16, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Seborrheic keratoses of florid eruption
Helen Gharwan1, Jeremy D Gradon
1Johns Hopkins University/Sinai Hospital of Baltimore, Department of Internal Medicine, Baltimore, Md., USA.
Abstract:
We report the case of a 79-year-old Caucasian man, who developed numerous pruritic seborrheic keratoses on his chest and back within one year. An underlying malignant disease was suspected. Upper and lower endoscopies were performed and the patient was diagnosed with adenocarcinoma of the ascending colon. We discuss the clinical significance of his cutaneous symptoms/signs, and review the medical literature on the paraneoplastic sign of Leser-Trélat.
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