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Related Concept Videos

Birth Control Methods01:22

Birth Control Methods

Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although vasectomy...
Infertility in Males01:23

Infertility in Males

Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Intrauterine Drug Delivery Systems01:21

Intrauterine Drug Delivery Systems

Controlled-release systems for intravaginal and intrauterine drug delivery have been developed primarily for the administration of contraceptive steroid hormones. These delivery routes circumvent first-pass hepatic metabolism, thereby enhancing bioavailability and allowing for reduced systemic dosages compared to oral administration. Such approaches contribute to improved therapeutic efficacy and patient compliance, particularly in long-term contraceptive regimens.Intravaginal Drug Delivery...
Gonadal and Placental Hormones01:24

Gonadal and Placental Hormones

The gonads, namely the testes in males and the ovaries in females, are pivotal in producing gonadal hormones that orchestrate the intricate processes of sexual development and reproduction.
In males, testosterone is the primary gonadal androgen. It plays a central role in the maturation of male reproductive organs — the penis and testes. Additionally, testosterone is instrumental in the development of secondary sexual characteristics — a deep voice as well as facial and pubic hair growth — and...
Testosterone: Functions and Regulation01:26

Testosterone: Functions and Regulation

The intricate hormonal interplay essential for male reproductive health begins with the release of gonadotropin-releasing hormone (GnRH) by the hypothalamus. This hormone prompts the pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). LH targets the Leydig cells in the testes, stimulating them to produce and release testosterone. In concert with testosterone, FSH acts on the Sertoli cells within the seminiferous tubules to facilitate the release of...

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Updated: May 16, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
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Published on: May 30, 2025

Demand for male contraception.

Emily Dorman1, David Bishai

  • 1Department of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Suite E4622, Baltimore, MD 21205, USA.

Expert Review of Pharmacoeconomics & Outcomes Research
|November 29, 2012
PubMed
Summary

Despite decades of research, no male contraceptive is available beyond condoms. This study explores male birth control research, challenges, and market potential for new methods.

Area of Science:

  • Reproductive Health
  • Contraception Development
  • Public Health Policy

Background:

  • The biological basis for male contraception is well-established, yet no viable alternatives to condoms exist.
  • Men currently rely on female-controlled methods, barrier methods, vasectomy, or abstinence for fertility control.
  • Pharmaceutical industry investment has declined, leaving non-profits and public entities to drive male contraceptive research.

Purpose of the Study:

  • To explore the historical developments and current challenges in male contraception research.
  • To provide preliminary market size estimates for a safe and effective male contraceptive.
  • To assess the potential market for novel male birth control methods.

Main Methods:

  • Review of historical and current male contraception research.

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  • Analysis of market demand forecasts and investment needs.
  • Preliminary market size estimation using available data.
  • Main Results:

    • Significant research progress has been made, but market entry remains a major hurdle.
    • Uncertainty in market demand and high costs for safety demonstration deter investment.
    • Preliminary data suggests a potential market for effective male contraceptives.

    Conclusions:

    • The development of male contraception faces significant financial and market challenges.
    • Continued investment and research are crucial to bring male contraceptive options to market.
    • Understanding market potential is key to attracting necessary funding for novel male methods.