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Updated: May 16, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Cardiological Society of India practice guidelines for angiography in patients with renal dysfunction
Insights
Coronary angiography (CAG) use is low in chronic kidney disease (CKD) patients due to contrast-induced acute kidney injury (CI-AKI) risks. New Indian guidelines aim to improve judicious CAG/PCI use for managing coronary artery disease (CAD) in CKD.
Area of Science:
- Cardiology
- Nephrology
- Medical Guidelines
Background:
- Coronary artery disease (CAD) is a leading cause of mortality in patients with chronic kidney disease (CKD).
- The risk of contrast-induced acute kidney injury (CI-AKI) deters the use of coronary angiography (CAG) in CKD patients, despite the high prevalence of CAD in this population.
- Existing guidelines for CAG/PCI in CKD are often not tailored to the Indian context.
Purpose of the Study:
- To develop evidence-based guidelines for the judicious use of CAG and percutaneous coronary intervention (PCI) in Indian patients with CKD.
- To assist physicians in selecting optimal management strategies for CAD in CKD patients relevant to the Indian healthcare setting.
Main Methods:
- A consensus-driven approach involving interventional cardiologists, nephrologists, and clinical cardiologists.
- Review and debate of existing data by an expert committee, including international experts.
- Iterative development and refinement of guidelines through teleconferences and circulated comments.
Main Results:
- The development of specific guidelines for CAG in renal dysfunction patients tailored for the Indian context.
- The guidelines were initially developed in 2010 and updated in 2012 by the Cardiological Society of India (CSI).
Conclusions:
- The established guidelines aim to address the underutilization of CAG/PCI in CKD patients with CAD.
- These guidelines provide a framework for better patient management, balancing the risks of CI-AKI with the high burden of CAD in CKD.
Abstract:
PREAMBLE: The potential risk of contrast-induced acute kidney injury (CI-AKI) has made utilization of coronary angiography in the work-up for the diagnosis of coronary artery disease in CKD quite low.(1) This is in contrast to increasing prevalence and severity of CAD as the serum creatinine rises.(2) In fact most CKD patients will succumb to CAD and not to ESRD.(3) Thus the judicious use of CAG/PCI in this setting is of prime importance but underused. The CSI began to develop guidelines for Indian context as most guidelines are those developed by ACC/AHA or ESC. The aim was to assist the physicians in selecting the best management strategy for an individual patient under his care based on an expert committee who would review the current data and write the guidelines with relevance to the Indian context. The guidelines were developed initially in June 2010 as an initiative of Delhi CSI. Three interventional cardiologist (SB, AS, KKS), one nephrologist (SCT) and two clinical cardiologists (ST, RG) along with Dr. Roxana Mehran (New York) and Dr. Peter McCullough (Missouri), U.S.A.; were involved in a three-way teleconference to discuss/debate the data. This was presented by SB, and over the next two hours each data subset was debated/agreed/deleted and this resulted in the "Guidelines for CAG in Renal Dysfunction Patients". These were then written and re- circulated to all for final comments. Further, these guidelines were updated and additional Task Force Members nominated by Central CSI were involved in the formation of the final CSI Guidelines. Both (Roxana Mehran and Peter McCullough) reviewed these updated Guidelines in October 2012 and after incorporating the views of all the Task Force members-the final format is as it is presented in this final document.
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