Related Experiment Video
Updated: May 16, 2026

Neural Stem Cell Transplantation in Experimental Contusive Model of Spinal Cord Injury
Published on: December 17, 2014
Stem cell repair of striatal ischemia
1Laboratory of Stem Cells and Restorative Neurology, Lund Stem Cell Center, University Hospital, Lund, Sweden. Zaal.Kokaia@med.lu.se
Abstract:
Stem cell-based approaches have promising prospects as new treatments to repair the stroke-damaged brain and promote efficient functional recovery. Studies in animal models of stroke have shown that transplantation of neural stem/progenitor cells (NSPCs) isolated from different sources can improve function not only by replacing dead neurons but also by trophic actions, modulation of inflammation, promotion of angiogenesis, and neuroprotection. Endogenous NSPCs produce new neurons following stroke and are also potential therapeutic targets. Joint efforts of basic researchers and clinicians are needed to develop safe and reproducible NSPC sources, test them in relevant animal models of stroke, and optimize the recovery of impaired functions.
Related Concept Videos
iPS Cell Differentiation
Stem Cell Therapy for Tissue Regeneration
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Tissue Renewal without Stem Cells
However, failure of such a system...
Neurogenesis and Regeneration of Nervous Tissue
