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Related Experiment Video

Updated: May 16, 2026

Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4
09:29

Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4

Published on: August 21, 2017

Transverse myelitis.

Shin C Beh1, Benjamin M Greenberg, Teresa Frohman

  • 1Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Neurologic Clinics
|November 29, 2012
PubMed
Summary
This summary is machine-generated.

Transverse myelitis (TM) is a spinal cord disorder causing weakness and sensory loss. This review covers its diverse causes, diagnosis, and management strategies for patients.

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Last Updated: May 16, 2026

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09:29

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Published on: August 21, 2017

Area of Science:

  • Neurology
  • Immunology
  • Pathobiology

Background:

  • Transverse myelitis (TM) is a neurological syndrome affecting the spinal cord.
  • It presents with acute or subacute dysfunction, including paresis and autonomic impairment.

Observation:

  • TM exhibits pathobiological heterogeneity.
  • Causes include infections, tumors, toxins, autoimmune disorders, and demyelinating diseases.

Findings:

  • This review details the clinical evaluation, diagnostic workup, and management of TM.
  • It differentiates TM from mimicking conditions and discusses various etiologies.

Implications:

  • Understanding TM's diverse causes is crucial for accurate diagnosis and treatment.
  • Effective management strategies are essential for patient recovery and long-term outcomes.