Related Experiment Video
Updated: May 16, 2026

Using Inducible Osteoblastic Lineage-Specific Stat3 Knockout Mice to Study Alveolar Bone Remodeling During Orthodontic Tooth Movement
Published on: July 21, 2023
[Space flight/bedrest immobilization and Bone. Exercise training for osteoporosis].
1Department of Physical Therapy, Faculty of Medical Technology, Niigata University of Health and Welfare/Division of Orthopedic Surgery, Niigata University and Dental Hospital, Japan.
Exercise therapy, including simple balance and strength exercises, can help prevent and treat osteoporosis by improving bone density and reducing fall risk in older adults. Combining exercises may yield better results for managing this locomotive syndrome.
Area of Science:
- Gerontology
- Orthopedics
- Physical Therapy
Context:
- Osteoporosis is a significant condition within the locomotive syndrome, impacting bone health and mobility.
- Exercise therapy is a cornerstone in managing osteoporosis, aiming to enhance bone mineral density and prevent falls.
- Specific, accessible exercises like single-leg standing and squatting are beneficial for the elderly population.
Purpose:
- To highlight the efficacy of exercise therapy in osteoporosis management.
- To recommend simple, safe exercises suitable for elderly individuals.
- To explore the potential benefits of combining different exercise modalities for improved outcomes.
Summary:
- Exercise therapy is crucial for osteoporosis prevention and treatment, improving bone mineral density and fall prevention.
- Recommended exercises include single-leg standing (eyes open, 1 minute) and "rokotore" squats, which are easily performed by older adults.
- Strengthening back muscles aids in preventing osteoporosis-related kyphosis (round back).
Impact:
- Suggests that a combination of these exercises could lead to enhanced therapeutic outcomes for osteoporosis.
- Provides practical, evidence-based exercise recommendations for elderly individuals at risk of or with osteoporosis.
- Contributes to the understanding of non-pharmacological interventions for locomotive syndrome management.
Related Concept Videos
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Fractures: Bone Repair
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...
Bone Remodeling
Bone Remodeling and Repair
Osteoclasts in Bone Remodeling
Hormones and Bone Tissue
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...