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Related Experiment Video

Updated: May 16, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
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Published on: December 9, 2022

Venous ulcers--an evidence-based update.

Marcia Spear1

  • 1Department of Plastic Surgery, Vanderbilt University Medical Center, Nashville, TN 37232, USA. marcia.spear@vanderbilt.edu

Plastic Surgical Nursing : Official Journal of the American Society of Plastic and Reconstructive Surgical Nurses
|November 29, 2012
PubMed
Summary
This summary is machine-generated.

Leg ulcers, primarily venous ulcers, affect about 1% of the US population. This review covers venous insufficiency, ulcer presentation, diagnosis, and treatments for chronic leg wounds.

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Procedure for Human Saphenous Veins Ex Vivo Perfusion and External Reinforcement
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Procedure for Human Saphenous Veins Ex Vivo Perfusion and External Reinforcement
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Procedure for Human Saphenous Veins Ex Vivo Perfusion and External Reinforcement

Published on: October 1, 2014

Area of Science:

  • Vascular Medicine
  • Dermatology
  • Wound Care

Background:

  • Leg ulceration is defined as chronic lower leg ulcers, excluding forefoot or toe lesions.
  • Venous stasis ulcers constitute 80-85% of leg ulcers, with a 1% prevalence in the US.
  • These ulcers disproportionately affect women and the elderly, often becoming chronic and recurrent.

Purpose of the Study:

  • To discuss the pathophysiology of venous insufficiency and ulcerations.
  • To outline the clinical presentation and diagnostic methods for leg ulcers.
  • To review current treatment strategies for venous leg ulcers.

Main Methods:

  • Literature review of venous insufficiency and leg ulceration.
  • Synthesis of information on pathophysiology, clinical features, and diagnosis.
  • Compilation of current treatment approaches.

Main Results:

  • Venous ulcers are the most common type, linked to venous insufficiency.
  • Complications can include cellulitis, osteomyelitis, and malignant transformation.
  • Effective management requires understanding pathophysiology and employing appropriate treatments.

Conclusions:

  • Venous leg ulcers are a significant health issue, particularly in older women.
  • Early diagnosis and comprehensive treatment are crucial for managing chronic venous ulcers.
  • Further research into advanced treatments may improve patient outcomes.