Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hyperthyroidism II: Pathophysiology01:27

Hyperthyroidism II: Pathophysiology

Hyperthyroidism is a hypermetabolic state caused by elevated levels of thyroid hormones, triiodothyronine (T3) and thyroxine (T4). It results from dysregulation at the thyroid, pituitary, or immune system level and affects multiple organ systems.PathophysiologyThe most common cause of hyperthyroidism is Graves’ disease, an autoimmune disorder in which antibodies, specifically thyroid-stimulating antibodies (TSAb), a subtype of TSH receptor antibodies (TRAb), bind to and activate TSH receptors...
Hyperthyroidism I: Introduction01:25

Hyperthyroidism I: Introduction

Hyperthyroidism is a type of thyrotoxicosis characterized by the thyroid gland's overproduction of the thyroid hormones triiodothyronine (T3) and thyroxine (T4). This hormone excess increases the basal metabolic rate and enhances sensitivity to catecholamines.DiagnosisDiagnosis is based on clinical features and biochemical testing. It typically shows suppressed thyroid-stimulating hormone (TSH) levels below 0.4 mIU/L, with elevated free T3 and/or T4. Additional tests, including thyroid...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association of Anxiety with Discrepancies Between Unattended and Attended Office Blood Pressure Measurement.

American journal of hypertension·2025
Same author

[Cataract surgery training in France: Analysis of the results of the European Board of Ophthalmology survey in the French cohort].

Journal francais d'ophtalmologie·2024
Same author

Quantification of contaminant mass discharge and uncertainties: Method and challenges in application at contaminated sites.

Journal of contaminant hydrology·2024
Same author

Graded or random - Effect of pore distribution in 3D titanium scaffolds on corrosion performance and response of hMSCs.

Biomaterials advances·2024
Same author

Training in cataract surgery in Spain: analysis of the results of a survey of the European Board of Ophthalmology in a Spanish cohort.

Archivos de la Sociedad Espanola de Oftalmologia·2024
Same author

The effect of heat stress on performance, fertility, and adipokines involved in regulating systemic immune response during lipolysis of early lactating dairy cows.

Journal of dairy science·2023

Related Experiment Video

Updated: May 16, 2026

Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma
04:01

Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma

Published on: September 15, 2023

Prophylactic central neck dissection for papillary thyroid cancer.

M Barczyński1, A Konturek, M Stopa

  • 1Third Department of General Surgery, Jagiellonian University Medical College, 37 Pradnicka Street, 31-202 Kraków, Poland. marbar@mp.pl

The British Journal of Surgery
|November 29, 2012
PubMed
Summary
This summary is machine-generated.

Prophylactic central neck dissection (CND) for papillary thyroid cancer (PTC) significantly improved long-term survival and locoregional control. This surgical approach did not increase the risk of permanent complications, making it a valuable option for PTC management.

More Related Videos

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
04:09

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter

Published on: September 20, 2024

Related Experiment Videos

Last Updated: May 16, 2026

Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma
04:01

Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma

Published on: September 15, 2023

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
04:09

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter

Published on: September 20, 2024

Area of Science:

  • Oncology
  • Surgical Oncology
  • Endocrinology

Background:

  • Prophylactic central neck dissection (CND) for papillary thyroid cancer (PTC) is a debated surgical strategy.
  • The study investigates the impact of CND on long-term outcomes in PTC patients.

Purpose of the Study:

  • To evaluate the effect of prophylactic CND on long-term survival and locoregional control in PTC patients.
  • To compare outcomes between patients who underwent total thyroidectomy (TT) with CND versus TT alone.

Main Methods:

  • Retrospective cohort study of 640 PTC patients undergoing TT.
  • Comparison between patients with TT and bilateral prophylactic CND versus TT without CND.
  • Personalized adjuvant radioiodine treatment was administered to both groups.

Main Results:

  • The 10-year disease-specific survival rate was higher in the CND group (98.0%) compared to the non-CND group (92.5%) (P=0.034).
  • Locoregional control rates at 10 years were improved with CND (94.5%) versus without CND (87.6%) (P=0.003).
  • CND was an independent predictor of improved locoregional control; extrathyroidal extension predicted recurrence. No significant differences in permanent hypoparathyroidism or recurrent laryngeal nerve injury were observed.

Conclusions:

  • Bilateral prophylactic CND for PTC staging, combined with personalized adjuvant radioiodine treatment, enhances 10-year disease-specific survival and locoregional control.
  • The study supports the use of prophylactic CND in PTC management without elevating the risk of permanent morbidity.