Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Intrauterine Drug Delivery Systems01:21

Intrauterine Drug Delivery Systems

Controlled-release systems for intravaginal and intrauterine drug delivery have been developed primarily for the administration of contraceptive steroid hormones. These delivery routes circumvent first-pass hepatic metabolism, thereby enhancing bioavailability and allowing for reduced systemic dosages compared to oral administration. Such approaches contribute to improved therapeutic efficacy and patient compliance, particularly in long-term contraceptive regimens.Intravaginal Drug Delivery...
Hypersensitivity Reactions: Delayed Hypersensitivity Reactions01:29

Hypersensitivity Reactions: Delayed Hypersensitivity Reactions

Delayed-Type Hypersensitivity (DTH), or Type IV hypersensitivity, is a cell-mediated immune response. It occurs when T cells, rather than antibodies, mediate a reaction to specific antigens. It is characterized by a delayed onset (1-2 days) and involves the recruitment of macrophages to the inflammation site.The initiation of a DTH response begins with the sensitization of T cells. During this phase, which lasts at least 1-2 weeks, antigen-specific T cells are activated, clonally expanded, and...
In Vitro Fertilization01:24

In Vitro Fertilization

In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
Drug Accumulation During Multiple Dosing: Intermittent IV Infusions01:24

Drug Accumulation During Multiple Dosing: Intermittent IV Infusions

Intermittent intravenous (IV) infusion is a method of drug administration where medications are delivered over short infusion periods followed by intervals of no drug delivery. This approach helps to prevent sustained high drug concentrations in the bloodstream, reducing the risk of adverse effects associated with prolonged exposure. Unlike continuous infusion, steady-state concentrations may not be achieved during a single dosing cycle but can be reached through repeated...
Transcytosis of IgG01:15

Transcytosis of IgG

Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
Oral Drug Delivery Systems: Delayed-Release Systems01:11

Oral Drug Delivery Systems: Delayed-Release Systems

Delayed-release drug delivery systems are specialized pharmaceutical formulations designed to postpone the release of active compounds until the drug reaches a specific region of the gastrointestinal (GI) tract, typically the intestine. These systems are essential for drugs that may cause gastric irritation, are unstable in acidic environments, or need to exert therapeutic effects locally in the intestinal or colonic regions.The core feature of delayed-release systems is the use of enteric...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clarification to HIVMA/IDSA HIV Primary Care Guidance Immunization Recommendations.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same author

Longitudinal antibody profiling after dengue reveals distinct dynamics by antibody specificity over 18 months.

Nature communications·2026
Same author

Striking a balance:Diagnostic performance of the ADNEX model at different risk thresholds.

European journal of obstetrics, gynecology, and reproductive biology·2026
Same author

Relationship Between Maternal Lipid Levels in Pregnancy and Major Congenital Malformations.

Journal of obstetrics and gynaecology of India·2026
Same author

Improving primary healthcare for non-communicable diseases during annual flooding in Bihar, India: study protocol for a hybrid implementation-effectiveness parallel cluster randomised controlled trial.

Trials·2026
Same author

Ultrafast MRI in BI-RADS 4 Masses: The Fast Lane to Clarity.

The Indian journal of radiology & imaging·2026

Related Experiment Video

Updated: May 16, 2026

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators
09:51

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators

Published on: March 21, 2018

Delayed interval delivery in a triplet gestation.

Rachel J Wooldridge1, Emily A Oliver, Tulika Singh

  • 1Department of Women's Health, Barts Health NHS Trust, Newham University Hospital, London, UK. racheljanewooldridge@doctors.org.uk

BMJ Case Reports
|November 29, 2012
PubMed
Summary
This summary is machine-generated.

This case study details managing a rare triamniotic trichorionic triplet pregnancy after one miscarriage. Interventions like rescue cerclage and progesterone successfully prolonged gestation, resulting in live births.

More Related Videos

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas
09:04

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas

Published on: September 5, 2011

Related Experiment Videos

Last Updated: May 16, 2026

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators
09:51

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators

Published on: March 21, 2018

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas
09:04

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas

Published on: September 5, 2011

Area of Science:

  • Maternal-Fetal Medicine
  • High-Risk Obstetrics

Background:

  • Triamniotic trichorionic triplet pregnancy is exceptionally rare.
  • Managing such pregnancies presents significant challenges, including high risks of preterm birth and fetal loss.

Observation:

  • A 27-year-old primigravida presented at 17 weeks gestation with a history of one fetal demise in a triamniotic trichorionic triplet pregnancy.
  • Initial assessment revealed no signs of preterm labor or infection.

Findings:

  • The patient underwent a rescue cerclage, received antibiotic prophylaxis, and daily progesterone suppositories.
  • Ultrasound monitoring of fetal growth and cervical length was performed every three weeks.
  • Corticosteroids were administered at 24 weeks for fetal lung maturity.
  • Delivery occurred at 31 weeks gestation via spontaneous rupture of membranes, active labor, and forceps delivery.
  • Both surviving neonates were born in good condition, requiring 72 hours of ventilatory support.

Implications:

  • This case highlights the successful application of a multimodal management strategy for a complex triplet pregnancy.
  • Interventions such as rescue cerclage, progesterone, and timely corticosteroid administration can improve perinatal outcomes in high-risk multiple gestations.
  • Further research into optimal management protocols for extremely rare multiple pregnancies is warranted.