Multiple myeloma presenting as hepatic nodular lesion.
Acta Clinica Belgica
|November 30, 2012
Summary
Multiple myeloma (MM) can infiltrate the liver, but a hepatic mass is rare. This case highlights a lambda light chain MM presenting as a large liver mass in an elderly male.
Area of Science:
- Hepatology
- Oncology
- Hematology
Background:
- Diffuse plasma cell infiltration of the liver is a known, though infrequent, complication of multiple myeloma (MM).
- Hepatic masses are an exceptionally rare presentation of MM.
Observation:
- A 75-year-old male presented with hepatomegaly and a large liver lesion.
- Diagnostic workup revealed a lambda light chain multiple myeloma associated with the hepatic mass.
Findings:
- The hepatic mass was confirmed to be a manifestation of lambda light chain multiple myeloma.
- This case represents an unusual focal presentation of MM within the liver.
Implications:
- This case underscores the importance of considering MM in the differential diagnosis of hepatic masses, even in the absence of typical myeloma symptoms.
- Further research into the mechanisms and management of focal hepatic MM is warranted.


