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Updated: May 16, 2026
High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC
Published on: February 2, 2024
[Chemical constituents of Centipeda minima]
1Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100700, China. caojunling72@163.com
Objective:
To study the chemical constituents from Centipeda minima.
Method:
The compounds were separated and purified by silica gel, reserved phase silica gel and Sephadex LH-20 gel column chromatography. Their structures were identified on the basis physicochemical property and spectral analysis.
Result:
Four chemical constituents were separated from ethyl acetate extracts and five chemical constituents were separated from n-butanol extracts of C. minima and identified as (2R,3R)-(+)-7,4'-di-O-methyldihydrokaempferol (1), iristectorin A (2), 4',5,8-trihydroxy-7-methoxyisoflavone (3), 3-trimethoxyquercetin (4), 3-O-caffeoyl-alpha-glueopyranose (5), 3-O-caffeoyl-beta-glucopyranose (6), quercetin (7), epipinoresinol (8) and hispidulin (9).
Conclusion:
Compounds 1-3, 5-6, 8 and 9 are separated from this genus for the first time.