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Obstructive sleep apnea hypopnea syndrome and metabolic syndrome: a synergistic cardiovascular risk factor

Becky Lynn Goodson1, Shu-Fen Wung, Kristen Hedger Archbold

  • 1Vista Medical Group, Mesa, Arizona, USA.

Journal of the American Academy of Nurse Practitioners
|November 30, 2012
PubMed

Insights

Metabolic syndrome and obstructive sleep apnea hypopnea syndrome (OSAHS) synergistically increase cardiovascular disease (CVD) risk. Early screening and integrated treatment, including CPAP, are crucial for managing this multiplied CVD risk.

Area of Science:

  • Cardiology
  • Sleep Medicine
  • Metabolic Disorders

Background:

  • Cardiovascular disease (CVD) is a leading cause of death in the US.
  • Metabolic syndrome and obstructive sleep apnea hypopnea syndrome (OSAHS) are independent CVD risk factors.
  • The interaction between OSAHS and metabolic syndrome on cardiovascular health is not fully understood.

Purpose of the Study:

  • To explore the physiological consequences of the interaction between OSAHS and metabolic syndrome on the cardiovascular system.
  • To review the current understanding of how these two conditions impact cardiovascular health.

Main Methods:

  • Literature search using keywords: "metabolic syndrome," "obstructive sleep apnea," "cardiovascular disease," "diabetes," "obesity," and "atherosclerosis."
  • Exclusion of studies involving pediatric populations.

Main Results:

  • Both metabolic syndrome and OSAHS significantly impact the cardiovascular system.
  • The combined presence of metabolic syndrome and OSAHS results in a synergistic increase in CVD risk.
  • Continuous positive airway pressure (CPAP) treatment can mitigate the overall cardiovascular risk burden.

Conclusions:

  • Routine screening for both metabolic syndrome and OSAHS is recommended for patients.
  • Integrated treatment approaches including CPAP, weight management, and other interventions are necessary.
  • Further research is needed to fully elucidate the mechanisms by which OSAHS and metabolic syndrome contribute to CVD.
Abstract

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