Complications of microwave hyperthermia treatment of psoriasis

Three healthy men with psoriatic plaques unresponsive to tar, anthralin, and UVB were treated with 2450 MHz microwave heating for 30 minutes at 42 degrees C. Two patients had plaques over bony prominences. Pain developed in both patients, and one had a hypotensive episode during the first treatment. The third patient, whose plaque was greater than 2 cm and was not located over a bony prominence, completed the 5 weeks of biweekly treatments with complete resolution of the plaque and no complications.