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Very long-term mortality after ischemic stroke: predictors of cardiovascular death

O M Rønning1

  • 1Medical Division, Department of Neurology, Akershus University Hospital, Lørenskog, Norway. ole.morten.ronning@ahus.no

Acta Neurologica Scandinavica. Supplementum
|November 30, 2012
PubMed

Insights

Key stroke predictors for long-term cardiovascular death include stroke severity, hemorrhagic stroke, diabetes, male gender, ischemic heart disease, and age. These factors significantly increase mortality risk post-stroke.

Area of Science:

  • Neurology
  • Cardiology
  • Public Health

Background:

  • Stroke is a leading cause of long-term disability and mortality.
  • Identifying predictors of long-term cardiovascular death after stroke is crucial for risk stratification and prevention.

Purpose of the Study:

  • To identify significant predictors associated with long-term mortality and cardiovascular death following an acute stroke.
  • To analyze risk factors contributing to cardiovascular mortality in a post-stroke cohort.

Main Methods:

  • A cohort of 550 acute stroke patients was followed for 12 years.
  • Mortality data was collected via linkage with national population and cause of death registers.
  • Cardiovascular deaths were identified using ICD-9 and ICD-10 codes.

Main Results:

  • Stroke severity, hemorrhagic stroke, diabetes, male gender, ischemic heart disease, age, and right hemispheric stroke were significant predictors of cardiovascular mortality.
  • The proportion of cardiovascular deaths in the cohort was 71% over the 12-year follow-up period.
  • Multivariate Cox regression analysis identified these factors with significant hazard ratios.

Conclusions:

  • Age, male gender, stroke severity, hemorrhagic stroke, diabetes, and ischemic heart disease are significant predictors of increased long-term cardiovascular mortality after stroke.
  • Atrial fibrillation, antihypertensive treatment, smoking, and living alone were not identified as risk factors for late cardiovascular deaths in this cohort.
  • These findings aid in understanding long-term risks and informing clinical management strategies for stroke survivors.
Abstract

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