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A simple method for measuring patient anti-globulin responses against isotypic or idiotypic determinants
S P Cobbold1, P R Rebello, H F Davies
1Department of Pathology, Cambridge University, U.K.
Journal of Immunological Methods
|February 20, 1990
Abstract:
A simple inhibition of capture enzyme-linked immunosorbent assay (IOC-ELISA) was developed which permitted the independent measurement of anti-idiotypic and anti-isotypic antiglobulins in serum samples from patients receiving therapeutic monoclonal antibodies.