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An unusual silicon mediated transannular cyclopropanation

Bing You1, Kate Hamer, William Lewis

  • 1School of Chemistry, University of Nottingham, University Park, UK.

Chemical Communications (Cambridge, England)
|November 30, 2012
PubMed
Summary

Researchers report a novel silicon-mediated reaction where a homoallylic nucleophile undergoes intramolecular conjugate addition, forming cyclopropanes. This method utilizes fluoride to transform dihydroazocinones into bicyclic compounds, expanding silicon chemistry.

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