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Familial migraine coma: a case study.

T F Münte1, H Müller-Vahl

  • 1Neurologische Klinik, Medizinische Hochschule, Hannover, Federal Republic of Germany.

Journal of Neurology
|February 1, 1990
PubMed
Summary
This summary is machine-generated.

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This study describes a rare malignant migraine syndrome causing coma, fever, and paralysis. Angiography may trigger attacks, so it should be avoided in affected individuals.

Area of Science:

  • Neurology
  • Genetics
  • Rare Diseases

Background:

  • Familial occurrence of rare neurological disorders.
  • Understanding migraine variants and their complications.

Observation:

  • A family presented with a rare malignant migraine syndrome.
  • Symptoms included recurrent coma, fever, meningitic signs, paresis, and persistent cerebellar deficits.
  • Coma episodes lasted days and were triggered by head trauma, exertion, and angiography.

Findings:

  • The described syndrome represents a distinct malignant migraine variant.
  • Cerebellar signs and neurological deficits were persistent.
  • Angiography was identified as a potential precipitating factor for coma attacks.

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Implications:

  • This syndrome warrants inclusion in the differential diagnosis for coma.
  • Medical professionals should exercise caution and avoid angiography in patients with this condition.
  • Further research into the genetic and pathogenic mechanisms of this rare migraine syndrome is needed.