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Emergency department visits in children with hemophilia
Bülent Özgönenel1, Ayesha Zia, Michael U Callaghan
1Division of Hematology/Oncology, Carman Ann Adams Children's Hospital of Michigan, Wayne State University, Detroit, Michigan 48201, USA. bulentozgonenel@yahoo.com
Insights
Pediatric emergency departments are vital for hemophilia care, managing bleeding, infections, and initial diagnoses. This study highlights their role in providing essential after-hours treatment and critical care for children with hemophilia.
Area of Science:
- Pediatric Emergency Medicine
- Hematology
- Pediatric Critical Care
Background:
- Pediatric emergency department (ED) management is crucial for hemophilia care.
- Bleeding and central venous catheter (CVC)-related infections are significant complications.
Purpose of the Study:
- To examine overall ED utilization by children with hemophilia.
- To investigate ED visits related to injury, bleeding, and CVC-related bloodstream infections.
Main Methods:
- Retrospective review of electronic medical records.
- Analysis of ED visits over a 5-year period (January 2006-December 2010).
Main Results:
- 536 ED visits from 84 male patients with hemophilia.
- Primary reasons for visits: injury/bleeding (61.2%), suspected CVC infection (11.8%).
- Intracranial hemorrhage occurred in 5 visits; 5.4% of visits were bloodstream infections.
Conclusions:
- Pediatric EDs are indispensable for hemophilia care.
- EDs manage life-threatening conditions like intracranial hemorrhage and CVC infections.
- EDs facilitate diagnosis in previously undiagnosed patients and provide after-hours care.
Background:
The pediatric emergency department (ED) management of bleeding and other complications of hemophilia constitutes an increasingly important component of hemophilia therapy. This retrospective study examined the overall ED use by children with hemophilia in a single center, with a particular aim to investigate visits related to injury or bleeding, and those related to blood stream infection in patients with a central venous catheter (CVC).
Methods:
Electronic medical records of patients with hemophilia presenting to Children's Hospital of Michigan ED were reviewed. Different categories of ED visits over a 5-year period (January 2006-December 2010) were examined.
Results:
There were 536 ED visits from 84 male patients (median age 4 years, range 0-21) with hemophilia over the 5-year period. The reasons for ED visits were: injury or bleeding (61.2%); suspected CVC-related infection (11.8%); causes unrelated to hemophilia (19.2%); and routine clotting factor infusion (7.8%). Eighteen visits from six patients were secondary to injury or bleeding in a patient not yet diagnosed with hemophilia. An intracranial hemorrhage was detected in five visits. Overall, 5.4% of all visits represented distinct episodes of bloodstream infection.
Conclusion:
The pediatric ED is an indispensable component of the overall hemophilia care, because: (1) patients with potentially lethal problems such as ICH or CVC-related infection may present to the ED for their initial management; (2) previously undiagnosed patients with hemophilia may also present to the ED for their first bleeding episodes, initiating the diagnostic investigations; (3) the ED provides after-hours treatment service for many episodes of injury or bleeding, and also for clotting factor infusion.
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