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Mouse dendritic cell (DC) influenza virus infectivity is much lower than that for human DCs and is hemagglutinin

Boris M Hartmann1, Wenjing Li, Jingjing Jia

  • 1Department of Neurology, Mount Sinai School of Medicine, New York, New York, USA.

Journal of Virology
|November 30, 2012
PubMed

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Influenza

Influenza is an acute, highly communicable viral disease that affects the respiratory tract and is responsible for seasonal epidemics worldwide. Influenza A is the most prevalent type associated with widespread outbreaks and is subtyped based on two surface glycoproteins: hemagglutinin (H) and neuraminidase (N), as in H1N1. These glycoproteins are essential for viral infectivity, transmission, and immune recognition. Transmission occurs primarily through respiratory droplets and contaminated...