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Related Concept Videos

Lipids as Anchors01:32

Lipids as Anchors

In the plasma membrane, the lipids forming the bilayer can also act as an anchor to tether proteins to the membrane. The three main types of lipid anchors found in eukaryotes are – prenyl groups, fatty acyl groups, and glycosylphosphatidylinositol or GPI groups. Prenyl and fatty acyl groups act as anchors on the cytosolic surface of the membrane, whereas GPI anchors proteins on the extracellular side.
The carboxy-terminal of most of the prenylated proteins, such as Ras proteins, contains the...
Membrane Fluidity01:26

Membrane Fluidity

Membrane fluidity is explained by the fluid mosaic model of the cell membrane, which describes the plasma membrane structure as a mosaic of components—including phospholipids, cholesterol, proteins, and carbohydrates—that gives the membrane a fluid character.
Mosaic nature of the membrane
The mosaic characteristic of the membrane helps the plasma membrane remain fluid. The integral proteins and lipids exist as separate but loosely-attached molecules in the membrane. The membrane is a relatively...
Membrane Fluidity01:23

Membrane Fluidity

Cell membranes are composed of phospholipids, proteins, and carbohydrates loosely attached to one another through chemical interactions. Molecules are generally able to move about in the plane of the membrane, giving the membrane its flexible nature called fluidity. Two other features of the membrane contribute to membrane fluidity: the chemical structure of the phospholipids and the presence of cholesterol in the membrane.
Membrane Asymmetry Regulating Transporters01:19

Membrane Asymmetry Regulating Transporters

Enzymes like flippase, floppase, and scramblase transfer phospholipids from one layer to another in the membrane, thereby affecting membrane asymmetry.
Flippase
Eukaryotic flippases are type-IV P-type ATPases or P4-ATPases belonging to P-type ATPase family proteins that are membrane-bound pumps involved in the ATP-mediated transport of ions and molecules across the membrane. Flippases flip specific phospholipids from the outer to the inner leaflet of a membrane. All P4-ATPases have one...
Membrane Proteins01:30

Membrane Proteins

Plasma membranes have integral transmembrane proteins involved in facilitated transport. These proteins are collectively referred to as transport proteins, and they function as either channels for the material or as carriers themselves. Channel proteins have hydrophilic domains exposed to the intracellular and extracellular fluids and a hydrophilic channel through their core that provides a hydrated opening for solutes to pass through the membrane layers. Passage through the channel allows...
Membrane Proteins01:30

Membrane Proteins

Plasma membranes have integral transmembrane proteins involved in facilitated transport. These proteins are collectively referred to as transport proteins, and they function as either channels for the material or as carriers themselves. Channel proteins have hydrophilic domains exposed to the intracellular and extracellular fluids and a hydrophilic channel through their core that provides a hydrated opening for solutes to pass through the membrane layers. Passage through the channel allows...

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Related Experiment Video

Updated: May 16, 2026

Lipid Droplet Isolation for Quantitative Mass Spectrometry Analysis
10:23

Lipid Droplet Isolation for Quantitative Mass Spectrometry Analysis

Published on: April 17, 2017

Lipid-transfer proteins.

Tzi Bun Ng1, Randy Chi Fai Cheung, Jack Ho Wong

  • 1School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China. b021770@mailserv.cuhk.edu.hk

Biopolymers
|November 30, 2012
PubMed
Summary
This summary is machine-generated.

Lipid-transfer proteins (LTPs) are versatile plant proteins involved in growth, defense, and environmental adaptation. Some LTPs also show potential in fighting human cancer and fungal infections.

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Area of Science:

  • Plant Biology
  • Biochemistry
  • Molecular Biology

Background:

  • Lipid-transfer proteins (LTPs) are abundant basic proteins in higher plants.
  • They are crucial for various plant processes including cutin formation, embryogenesis, and defense.
  • LTPs contribute to plant adaptation to environmental stresses and symbiosis.

Purpose of the Study:

  • To review the diverse roles and functions of Lipid-transfer proteins (LTPs) across the plant kingdom.
  • To highlight the significance of LTPs in plant physiology and development.
  • To explore the potential applications of plant-derived LTPs.

Main Methods:

  • Literature review of scientific articles on plant Lipid-transfer proteins.
  • Analysis of published data on LTP functions in different plant species.
  • Compilation of information on the biochemical and physiological roles of LTPs.

Main Results:

  • LTPs are involved in structural roles like cutin formation.
  • They participate in plant defense mechanisms against pathogens.
  • Specific LTPs demonstrate antiproliferative effects on cancer cells and antifungal activity against human pathogens.

Conclusions:

  • Lipid-transfer proteins (LTPs) are multifunctional proteins essential for plant life.
  • Their roles extend beyond basic physiology to include potential therapeutic applications.
  • Further research into plant LTPs could yield novel applications in medicine and agriculture.