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Skin Cancer

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Updated: May 16, 2026

A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds

A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds

Published on: February 23, 2024

[Malignant wounds].

Mirna Situm¹, Maja Kolić

¹Sestre milosrdnice University Hospital Center, University Department of Dermatovenereology Zagreb, Croatia.

Acta Medica Croatica : Casopis Hravatske Akademije Medicinskih Znanosti

|December 1, 2012

Summary

Malignant wounds, often caused by skin cancer or metastases, require prompt biopsy for diagnosis. Early detection of these complex wounds is crucial to prevent poor prognosis and metastasis.

Area of Science:

Dermatology
Oncology
Pathology

Context:

Malignant wounds are atypical and arise from primary skin tumors, cutaneous metastases, or paraneoplastic syndromes.
Basal cell carcinoma, squamous cell carcinoma, and melanoma are common malignant skin tumors that can ulcerate.
Melanoma is the leading cause of cutaneous metastases, accounting for 40% of all skin metastases.

Purpose:

To highlight the importance of considering malignant processes in non-healing chronic wounds.
To emphasize the diagnostic role of biopsy and histopathologic analysis.
To underscore the risks associated with delayed diagnosis of malignant wounds.

Summary:

Malignant wounds stem from various cancer-related processes affecting the skin.
Key differential diagnoses include basal cell carcinoma, squamous cell carcinoma, melanoma, and Kaposi sarcoma.

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Biopsy is essential for persistent chronic wounds lacking healing potential to rule out malignancy.

Impact:

Timely diagnosis of malignant wounds improves patient prognosis.
Early intervention can prevent limb loss and the spread of metastases.
Recognizing malignant wounds is critical for effective cancer management and patient outcomes.