Related Experiment Video
Updated: May 16, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
[Wounds in children and Epidermolysis bullosa]
Nives Pustisek1, Irena Babić, Antun Kljenak
1Sestre milosrdnice University Hospital Center, University Department of Pediatrics, Zagreb, Croatia. nives.pustisek@kbcsm.hr
Abstract:
Epidermolysis bullosa is a group of inherited disorders characterized by blister formation on the skin and mucous membrane as the result of molecular defects in genes coding for different structural proteins. They present with a wide clinical spectrum of manifestations because of a variety of molecular defects. Therapy depends on the form of the disease, severity and extent of skin involvement and extracutaneous manifestations, and consists of supportive skin care and supportive care for other organ systems. Skin care includes protection against trauma, proper skin care, treatment of blisters and erosions, and regular dermatological controls for early detection of skin cancer.
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