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Nonossifying fibroma presenting as an aneurysmal bone cyst: a case report
Akio Sakamoto1, Takeaki Ishii, Yoshinao Oda
1Department of Orthopaedic Surgery, National Hospital Organization Kokura Medical Center, Kitakyushu, Fukuoka, Japan. akio@med.kyushu-u.ac.jp.
Journal of Medical Case Reports
|December 1, 2012
Summary
Nonossifying fibroma can rarely develop into an aneurysmal bone cyst. This case highlights the possibility of this association, even in atypical diaphyseal locations of long bones.
Area of Science:
- Pediatric Orthopedics
- Skeletal Radiology
- Bone Pathology
Background:
- Nonossifying fibroma is a common benign bone lesion in children, typically found in long bone metaphyses.
- Aneurysmal bone cysts are less common and characterized by blood-filled spaces.
- Secondary aneurysmal bone cyst formation from nonossifying fibroma is a rare occurrence.
Purpose of the Study:
- To report a rare case of secondary aneurysmal bone cyst formation in a nonossifying fibroma.
- To emphasize the diagnostic challenges posed by atypical locations and secondary changes.
- To raise awareness among clinicians regarding this rare association.
Main Methods:
- Case presentation of a 13-year-old boy with thigh discomfort and a femoral lesion.
- Radiographic and MRI evaluation showing an expanding osteolytic lesion.
- Surgical intervention (curettage and bone graft) with pathological confirmation.
Main Results:
- The lesion was initially identified as an osteolytic lesion in the femoral diaphysis.
- The lesion enlarged over 10 months, with no solid areas detected on MRI.
- Pathology confirmed a blood-filled cystic lesion with a nonossifying fibroma wall, indicating secondary aneurysmal bone cyst formation.
Conclusions:
- Nonossifying fibroma can rarely be associated with secondary aneurysmal bone cyst formation.
- The diaphyseal location of nonossifying fibroma is atypical but possible.
- This case underscores the importance of considering rare diagnoses in challenging presentations.
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