The relationship between some of the cardiovascular risk factors and arterial stiffness parameters in essentially

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Measuring the Carotid to Femoral Pulse Wave Velocity (Cf-PWV) to Evaluate Arterial Stiffness
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Measuring the Carotid to Femoral Pulse Wave Velocity (Cf-PWV) to Evaluate Arterial Stiffness

Published on: May 3, 2018

Battal Altun1, Fatih Bulucu, Seref Demirbas

  • 1Department of Internal Medicine, Guflhane Medical Academy , Ankara , Turkey.

Clinical and Experimental Hypertension (New York, N.Y. : 1993)
|December 1, 2012
PubMed

Insights

In hypertensive women, higher augmentation index and central aortic pressure indicate increased arterial stiffness. These findings suggest sex hormones play a role in atherosclerosis development in women.

Area of Science:

  • Cardiovascular Medicine
  • Endocrinology
  • Vascular Biology

Background:

  • Hypertension is linked to endothelial dysfunction.
  • Arterial stiffness is a key indicator of cardiovascular risk.
  • Understanding sex differences in hypertension is crucial for targeted therapies.

Purpose of the Study:

  • To investigate the relationship between cardiovascular risk factors and arterial stiffness parameters in hypertensive patients.
  • To explore potential sex-based differences in arterial stiffness.

Main Methods:

  • Study included 109 hypertensive patients (63 female, 46 male).
  • Arterial stiffness was assessed using pulse wave velocity, augmentation index, and central aortic pressure.
  • Statistical analysis compared parameters between sexes.

Main Results:

  • Augmentation index was significantly higher in women (P < .001).
  • Central aortic pressure was significantly higher in women (P = .03).
  • Women exhibited greater arterial stiffness than men.

Conclusions:

  • Hypertensive women show increased arterial stiffness compared to men.
  • These findings highlight the potential influence of sex hormones on atherosclerosis pathogenesis in women.
  • Further research into sex-specific cardiovascular risk management is warranted.

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