Related Experiment Video
Updated: May 16, 2026

Lavage-induced Surfactant Depletion in Pigs As a Model of the Acute Respiratory Distress Syndrome (ARDS)
Published on: September 7, 2016
Fluid recovery during lung lavage in meconium aspiration syndrome
Peter A Dargaville1, Beverley Copnell, John F Mills
1Department of Paediatrics, Royal Hobart Hospital and University of Tasmania, Hobart, Tas., Australia. peter.dargaville@dhhs.tas.gov.au
Unlabelled:
Lung lavage using two aliquots of 15 mL/kg of dilute surfactant was performed in 30 ventilated infants with severe meconium aspiration syndrome (MAS). Mean recovery of instilled lavage fluid was 46%, with greater fluid return associated with lower mean airway pressure at 24 h and a shorter duration of respiratory support.
Conclusion:
Recovery of instilled lavage fluid is paramount in effective lung lavage in MAS and must be afforded priority in the lavage technique.
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