Related Experiment Video
Updated: May 16, 2026

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents (HPHC)
Published on: May 10, 2016
Toxicity and safety evaluation of boswellic acids
1Department of Pharmacology, Regional Research Laboratory, Canal Road, Jammu-Tawi 180 001, India.
Abstract:
The acute, sub-acute and chronic toxicity studies on boswellic acids (BAs) were carried out on mice, rats and monkeys. BAs did not cause any mortality in rats and mice when administered orally and intraperitoneally in doses up to 2 g/kg. Daily oral administration of BAs in three doses (low and very high) to rats and monkeys revealed no significant changes in general behaviour, or clinical, haematological, biochemical and pathological data. BAs, therefore, can be regarded as safe for clinical studies.
Related Concept Videos
Bioactivation and Tissue Toxicity
Toxicity Testing in Animals
Drug Toxicity: Overview
Drug Toxicity: Risk factors
Drug Toxicity: Dose-Dependent Reactions
Phase II Reactions: Glutathione Conjugation and Mercapturic Acid Formation
Several distinctive characteristics distinguish glutathione conjugation from other phase II...
