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Updated: May 16, 2026
In Vivo Infection with Leishmania amazonensis to Evaluate Parasite Virulence in Mice
Published on: February 20, 2020
In vitro and in vivo leishmanicidal studies of Peperomia galioides (Piperaceae)
A Fournet1, M E Ferreira, A Rojas de Arias
1ORSTOM (Institut Français de Recherche Scientifique pour le Développement en Coopération), Asuncion, Paraguay.
Abstract:
Petroleum ether and methylene chloride extracts of Peperomia galioides and three prenylated diphenols, grifolic acid, grifolin and piperogalin exhibited in vitro antileishmanial activity. During the course of infection of BALB/c mice with Leishmania amazonensis, the treatments with each of these compounds did not influence the progression of the disease.
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