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Construction of best confidence intervals for half-lives
1Department of Statistics, Ohio State University, Columbus 43210.
Journal of Veterinary Pharmacology and Therapeutics
|March 1, 1990
Abstract:
This paper presents a method of determining a confidence interval for the drug half-life based on statistical properties of the estimates of the disappearance rate constant of the drug. This interval is shown to be of minimum length which indicates it is a more precise estimate than others currently in use. A computer program to construct these intervals is available upon request.