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Prosthetic aortic valve endocarditis due to Ochrobactrum anthropi
Shashikala Shivaprakasha1, Sanjay Rajdev, Harminder Singh
1Department of Laboratory Medicine and Microbiology, SevenHills Hospital, Mumbai, India.
Abstract:
Ochrobactrum anthropi is an emerging pathogen increasingly affecting the immunocompromised host. Only four cases of infective endocarditis have been documented in literature. Therapeutic approach is a rising challenge as it is resistant to most of the currently available beta lactam antibiotics with the exception of carbapenems. We report a case of prosthetic valve endocarditis secondary to Ochrobactrum anthropi infection; the host was temporarily immunocompromised due to disseminated herpes zoster after surgery.
Insights
Ochrobactrum anthropi is an emerging pathogen causing rare cases of infective endocarditis. This case highlights challenges in treating prosthetic valve endocarditis due to antibiotic resistance.
Area of Science:
- Infectious Diseases
- Microbiology
- Cardiology
Background:
- Ochrobactrum anthropi is an emerging opportunistic pathogen.
- Infective endocarditis is a rare but serious complication.
- Antibiotic resistance, particularly to beta-lactams, poses therapeutic challenges.
Observation:
- A case of prosthetic valve endocarditis caused by Ochrobactrum anthropi is presented.
- The patient was temporarily immunocompromised due to disseminated herpes zoster post-surgery.
Findings:
- Ochrobactrum anthropi demonstrated resistance to common beta-lactam antibiotics.
- Carbapenems were effective in this case.
- Successful management of prosthetic valve endocarditis in an immunocompromised host.
Implications:
- Highlights the need for vigilance regarding Ochrobactrum anthropi infections in vulnerable patients.
- Underscores the importance of antimicrobial susceptibility testing for effective treatment.
- Informs therapeutic strategies for rare infective endocarditis cases.
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