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Updated: May 16, 2026

Is My Mouse Pregnant? High-Frequency Ultrasound Assessment
Published on: March 18, 2021
[Pregnancy of unknown location]
Monia Malek-Mellouli1, Fethi Ben Amara, Hedi Reziga
1Centre de Maternite et de neonatologie de Tunis, La Rabta, Tunisie.
Background:
A pregnancy of unknown location is a descriptive term that can be defined after performing trans vaginal ultrasound. This situation includes patients with a positive pregnancy test but with no evidence of intra or extra uterine pregnancy on transvaginal sonography.
Aim:
To discuss different aspects of management of women with pregnancy of unknown location.
Methods:
Review of the literature.
Results:
Serum human chorionic gonadotrophin levels, progesterone levels and mathematical models are helpful in the prediction of final outcome of pregnancy: intra uterine pregnancy, ectopic pregnancy, spontaneous resolution or persistent pregnancy of unknown location. Active expectant management of asymptomatic women with a pregnancy of unknown location has been shown to be safe.
Conclusion:
Surgical intervention (diagnostic laparoscopy and uterine curettage) to diagnose the location of the pregnancy should be restrictive.
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